%%EOF The “UN Sub-committee of Experts on Transport of Dangerous Goods” decided in July 1994 to remove Diphenylmethane Diisocyanate (MDI) from the list of hazardous goods. Details of dossier compliance checks and testing proposal evaluation. This section provides links to the list of precautions (precautionary statements) and to the guidance on safe use, if they have been provided in REACH registration dossiers. This section provides an overview of the calculated volume at which the substance is manufactured or imported to the European Economic Area (EU28 + Iceland, Liechtenstein and Norway). This substance is registered under the REACH Regulation and is manufactured in and / or imported to the European Economic Area, at ≥ 100 000 per annum. Hazardous Substances - Art. 0 Biocidal Products Committee opinions on active substance approval, National authorisation and mutual recognition, Understanding the Waste Framework Directive, Tools to prepare and submit SCIP notifications, List of substances subject to the POPs Regulation, Draft recommendation for inclusion in the Authorisation List and consultation, Submitted restrictions under consideration, Harmonised classification and labelling targeted consultations, Consultations on ECHA Executive Director’s requests, PACT - Public Activities Coordination Tool, Information on Candidate List substances in articles, Candidate List of substances of very high concern for Authorisation, Registry of restriction intentions until outcome, Registry of SVHC intentions until outcome, Table of harmonised entries in Annex VI to CLP, Occupational exposure limits - Activity list, Harmonised classification and labelling (RAC), Chapter R.12: Use Descriptor system of ECHA Guidance on information requirements and chemical safety assessment, Candidate list of substances of very high concern for authorisation, Guidance on the safe use of the substance, PACT - Public activities Co-ordination Tool, Persistence, bioaccumulation and toxicity assessment, RMOA - Regulatory Management Options Analysis, CAD - Chemical Agents Directive,Art. 92/85/EEC on Pregnant Workers, 28 November 1992 (updated by table 3 of Annex VI to CLP, 5 Oct 2018), EU. 0.07 STEL . 590 Revision Date: 1/8/2019 Version: 10.0 GHS Compliant . Precautionary statements - describe recommended measures to minimise or prevent adverse effects resulting from exposure to a hazardous product or improper storage or handling of a hazardous product. National Center for Environmental Assessment, Office of Research and Development, … Substances indicated, in 2009, as being intended to be registered by at least one company in the EEA. Environmental Protection Agency. The EC Inventory is a combination of three independent European lists of substances from the previous EU chemicals regulatory frameworks (EINECS, ELINCS and the NLP-list). IDH number: 1506861 Product name: LOCTITE HB E202 known as PURBOND HB E202 Page 6 of 6 International Air Transportation (ICAO/IATA) The described Product category (i.e. This section highlights four regulatory activities or outcomes under REACH – Registration, Evaluation, Authorisation and Restriction of Chemicals – Regulation (EC) No 1907/2006: Please note: The identification of relevant regulatory activities and outcomes is done automatically and without manual verification. The molecular formula identifies each type of element by its chemical symbol and identifies the number of atoms of each element found in one discrete molecule of the substance. The ‘Hazard classification’ and labelling section uses the signal word, pictogram(s) and hazard statements of the substance under the harmonised classification and labelling (CLH) as its primary source of information. Methylenediphenyl diisocyanate (MDI) including the following specific isomers (See group members): Previous consultations on ECHA’s Executive Director Requests to the Committees, Applications for authorisation consultations, Harmonised classification and labelling consultations, ECHA Executive Director’s requests related to the CLH process, Consultation on potential candidates for substitution, Consultation on derogation to the exclusion criteria, ECHA's Executive Director Requests to the Committees, Consultation on a draft recommendation for amendment of Authorisation List entries, Consultations in the authorisation process, Occupational exposure limits - Call for comments and evidence, Occupational exposure limits - Previous calls for comments and evidence, Occupational exposure limits – Consultations on OEL recommendation, Derogations for the protection of cultural heritage, ECHA's current activities on restrictions, ECHA's completed activities on restriction, Information on Candidate List substances in articles table, Information from the Existing Substances Regulation (ESR), PBT/vPvB assessments under the previous EU chemicals legislation, Adopted opinions and previous consultations on applications for authorisation, Adopted opinions on restriction proposals, Mapping exercise – Plastic additives initiative, Occupational exposure limits substance evaluations, List of substances subject to POPs Regulation, Small and Medium-sized Enterprises (SMEs), Practical examples of chemical safety reports. In order to process your orders without delay, we request that you provide the required business documentation to purchase this product. Substances for which an agreed set of classification and labelling data has been agreed at EU level by Member States. REACH registration dossiers have greater data requirements (such as supporting studies) than do notifications under CLP. This Action Plan addresses the use of methylene diphenyl diisocyanate (MDI) and related compounds (See Appendix 1) in products that may result in consumer and general population Table 3 of Annex VI to CLP Regulation); and (2) the Candidate List of substances of very high concern (SVHC). First-aid measures The ‘Properties of concern’ section shows ECHA-assigned graphical indicators for certain substance properties that are regarded as being of relevance or importance to human health and/or the environment based on the information provided to the Agency. The EC or list number is the primary substance identifier used by ECHA. This substance has been identified as member of the following groups of substances: Welcome to the ECHA website. Methylene-diphenyl-diisocyanate (MDI) 101-68-8 OSHA PEL-TWA 0.02 ppm ACGIH TLV -TWA 0.005 ppm 2 In AFL-CIO v. OSHA 965 F. 2d 962 (11th Cir. InfoCards are updated when new information is available. Substances intended to be restricted and entered in Annex XVII to REACH. LEL:. Methylene diphenyl diisocyanate (MDI) in commercial form typically exists as a mixture of 4,4'-MDI (monomer) and certain oligomers of MDI (Encyclopedia of Chemical Technology, 1983). The CLP Regulation ensures that the hazards presented by chemicals are clearly communicated to workers and consumers in the European Union through classification and labelling of chemicals. It does not represent a new labelling, classification or hazard statement, neither reflect other factors that affect the susceptibility of the effects described, such as duration of exposure or substance concentration (e.g. the electronic edition of the Official Journal of the European Union. Methylenedi-p-phenyl diisocyanate 0.005 ppm TWA 0.005 ppm TWA; 0.05 mg/m3 TWA 75 mg/m3 IDLH 0.02 ppm Ceiling; 0.2 mg/m3 Ceiling Diphenylmethane-2,4'-diisocyanate none listed none listed none listed 2,6-Di-tert-butyl-p-cresol 2 mg/m3 TWA (inhalable fraction and vapor) 10 mg/m3 TWA none listed This information is only displayed if the substance is well–defined, its identity is not claimed confidential and there is sufficient information available in ECHA’s databases for ECHA’s algorithms to generate a molecular structure. ��#�Y^�7��b�4.F��}��:WI���1w�y�(_W�q2.H�������e�B�r�|�I��|>�Ք^ Gtb�+������Ϸ�9z�W�D����4N��.H�B����+�-�J��t|Rw�����. Methylenediphenyl 4,4'-Diisocyanate . Substances potentially subject to further regulatory management. ECHA organises consultations to get feedback from all interested parties and to gather the widest possible range of scientific information for the regulatory processes. Methylene Diphenyl Diisocyanate (monomeric MDI) and polymeric MDI (PMDI) CASRN 101-68-8, 9016-87-9 | DTXSID7025180 Such notifications are required for hazardous substances, mixtures, or articles, manufactured or imported at over 1 kg per annum. Methylene diphenyl diisocyanate Prevent eye contact Wash skin: Linking to a non-federal website does not constitute an endorsement by CDC or any of its employees of the sponsors or the information and 101-8-8 … 2(b)(i) - Hazardous Agents, Cosmetic Products Regulation, Annex II - Prohibited Substances, EU Ecolabels - Restrictions for Hazardous Substances/Mixtures, FCM and Articles Regulation, Annex I - Authorised Substances, Protection of Pregnant and Breastfeeding Workers Directive, Annex I+II, Workplace Signs - minimum requirements & signs on containers and pipes, Waste Framework Directive, Annex III - Waste - Hazardous Properties, Fertiliser Regulation- Annex I, E.3 (chelating and complexing agents), Substances of very high concern identification, Recommendation for the Authorisation List, Getting started with EU chemicals legislation, Classification of substances and mixtures, Harmonised classification and labelling (CLH). Guidance To help minimize the formation of a dimer, an insoluble white solid that may impact the quality of the product, 4,4’-methylene diphenyl diisocyanate (MDI) is usually stored and transported in drums at temperatures below 41°F (5°C). Brain injury, 8(3):285–294. This substance is used for the manufacture of: machinery and vehicles. 7 and points 2 and 3 of the Annex to Directive 94/33/EC, to which young persons (under 18 years of age) may not be exposed at the workplace. Toluene Diisocyanate (TDI) is classified and regulated as hazardous for handling and transport. If generated, an InChI string will also be generated and made available for searching. … The annexes to this directive provide detailed information about the minimum requirements for all safety and health signs. The freezing point of 4,4’ … Release to the environment of this substance can occur from industrial use: manufacturing of the substance, formulation of mixtures and for thermoplastic manufacture. Substances which have been registered and can be placed on the EEA market by those companies with a valid registration. C&L Inventory . Substances listed in the EINECS, ELINCS, or NLP inventories. The source of the information is mentioned in the introductory sentence of the hazard statements. This list contains substances to which pregnant workers and workers who have recently given birth or are breastfeeding may not be exposed. Chemical name CAS number % Methylene diphenyl 101-68-8 >1 diisocyanate O-(p-isocyanatobenzyl)phenyl 5873-54-1 >1 Isocyanate Composition comments All concentrations are in percent by weight unless ingredient is a gas. 1992), the court overturned OSHA’s 1989 Air Contaminants Rule, including the This list contains biological and chemical agents, in accordance with Art. Note that this list is not exhaustive. According to the annexes to the directive, storage areas and containers containing chemical substances or mixtures that are classified as hazardous according to the CLP Regulation (1272/2008/EC) must be marked and/or labeled. Emergency Response Guidebook 2016. CAS Number 101-68-8 Synonym(s) p,p'-Diphenylmethane diisocyanate; p,p'-Methylenebis[phenyl isocyanate]; Bis(p-isocyanatophenyl)methane; Diphenylmethane diisocyanate; Diphenylmethane p,p'-diisocyanate; Methylenebis[p-phenyl isocyanate]; 4,41-MDI; MDI; Monomeric MDI; NCI-C50668 ... Reference Exposure Levels for Methylene Diphenyl Diisocyanate … If the substance was not covered by the EC Inventory, ECHA attributes a list number in the same format, starting with the numbers 6, 7, 8 or 9. 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